Janneke graduated cum laude in medicine from the University of Amsterdam in 1994. She performed her PhD in 2001.
For this PhD she investigated the neuroprotective effect of calcium antagonists in stroke. She became a neurologist and after that completed training for intensive care leading to a registration as neurologist-intensivist in 2005. Currently she is working at the Intensive care unit of the Academic Medical Center in Amsterdam, the Netherlands. Her special interest is diminishing brain injury after cardiac arrest and optimal prognostication in patients with postanoxic coma. She is (co-)author of more than 130 manuscripts in peer-reviewed journals. In 2013 she was nominated Principal Investigator in her academic center. She was part of the steering group of the international multicenter study group on target temperature management (TTM trial) after cardiac arrest. Finally she was involved in the international recommendation on prognosis after cardiac arrest.