Cacha is working as a pediatric neurologist at Leiden University Medical Center. Her special interest is fetal and neonatal neurology and she has been the driving force behind Neurophyxia since the inception of the project, which started during her PhD. She investigated potential neuroprotective strategies following neonatal hypoxia-ischemia, and identified 2-iminobiotin as a potential neuroprotective drug. From the founding of Neurophyxia she was Chief Scientific Officer. From November 2017 untill May 2018, she was the CEO of Neurophyxia.